A process of GENETIC TRANSLATION whereby the formation of a peptide chain is started.
It includes assembly of the RIBOSOME components, the MESSENGER RNA coding for the
polypeptide to be made, INITIATOR TRNA, and PEPTIDE INITIATION FACTORS; and placement
of the first amino acid in the peptide chain. The details and components of this process
are unique for prokaryotic protein biosynthesis and eukaryotic protein biosynthesis
Note générale sur le champ d'application :
coordinate with specific peptide; for protein biosynthesis on the ribosome only; for
non-ribosomal biosynthesis use PEPTIDE BIOSYNTHESIS, NUCLEIC ACID-INDEPENDENT