A family of intracellular CYSTEINE ENDOPEPTIDASES that play a role in regulating INFLAMMATION
and APOPTOSIS. They specifically cleave peptides at a CYSTEINE amino acid that follows
an ASPARTIC ACID residue. Caspases are activated by proteolytic cleavage of a precursor
form to yield large and small subunits that form the enzyme. Since the cleavage site
within precursors matches the specificity of caspases, sequential activation of precursors
by activated caspases can occur
Note générale sur le champ d'application :
CASPASES, EFFECTOR and CASPASES, INITIATOR and specifics are available
Qualificatifs autorisés : IP / IM / PK / BI / PH / TU / BL / CF / CS / DF / CH / DE
/ UR / RE / HI / AN / CL / EC / GE / PD / ST / AD / SD / UL / PO / AE / TO / ME99
Informations sur la notice
Identifiant de la notice : 040845087
RCR créateur de la notice : 0001
Date de création : 23-09-1998
RCR dernier modificateur de la notice : 1999
Date de dernière modification : 20-03-2024 à 17 h 17