Documentation Documentation
Identifiant pérenne de la notice : 040837386Copier cet identifiant (PPN)
Notice de type FMeSH

Point d'accès autorisé

NADPH oxidase

Variantes de point d'accès

Oxidases, NADPH
[Nom commun]
NAD(P)H oxidase
[Nom commun]
NADPH Oxidase
[Nom commun]
Oxidase, NADPH
[Nom commun]
Nox Proteins
[Nom commun]
NAD(P)H Oxidases
[Nom commun]


Note publique d''information : 
A family of membrane-associated flavoprotein NADPH-dependent oxidoreductases that catalyze the univalent reduction of OXYGEN to create SUPEROXIDES. Structurally, they are characterized by six N-terminal transmembrane ALPHA-HELICES, a FLAVIN-ADENINE DINUCLEOTIDE (FAD)-binding region, and a C-terminal NADPH-binding region. They are expressed primarily by EPITHELIAL CELLS in gut, kidney, colon, and smooth muscle tissues, as well as GRANULOCYTES and function to transfer electrons across membranes to molecular oxygen. Defects in the production of superoxide ions by some NADPH oxidases result in GRANULOMATOUS DISEASE, CHRONIC

Notice d'autorité liée

Point d'accès autorisé parallèle

NADPH Oxidases

Identifiants externes

Identifiant MeSH : mesD019255

Utilisation dans FMeSH

Qualificatifs autorisés : IP / IM / PK / BI / PH / TU / BL / CF / CS / DF / CH / DE / UR / RE / HI / AN / CL / EC / GE / PD / ST / AD / AI / SD / UL / PO / AE / TO / ME2018 (1997)

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