A biosensing technique in which biomolecules capable of binding to specific analytes
or ligands are first immobilized on one side of a metallic film. Light is then focused
on the opposite side of the film to excite the surface plasmons, that is, the oscillations
of free electrons propagating along the film's surface. The refractive index of light
reflecting off this surface is measured. When the immobilized biomolecules are bound
by their ligands, an alteration in surface plasmons on the opposite side of the film
is created which is directly proportional to the change in bound, or adsorbed, mass.
Binding is measured by changes in the refractive index. The technique is used to study
biomolecular interactions, such as antigen-antibody binding
Note générale sur le champ d'application :
do not confuse with plasmon, extrachromosomal genetic material
Point d'accès autorisé parallèle
Surface Plasmon Resonance
Identifiants externes
Identifiant MeSH : mesD020349
Utilisation dans FMeSH
Qualificatifs autorisés : CL / EC / HI / IS / MT / ST / TD / VE / SN / ES99
Informations sur la notice
Identifiant de la notice : 040845699
RCR créateur de la notice : 0001
Date de création : 23-09-1998
RCR dernier modificateur de la notice : 4994
Date de dernière modification : 20-03-2024 à 10 h 18