Screening techniques first developed in yeast to identify genes encoding interacting
proteins. Variations are used to evaluate interplay between proteins and other molecules.
Two-hybrid techniques refer to analysis for protein-protein interactions, one-hybrid
for DNA-protein interactions, three-hybrid interactions for RNA-protein interactions
or ligand-based interactions. Reverse n-hybrid techniques refer to analysis for mutations
or other small molecules that dissociate known interactions
Note publique d''information :
Variations on the two-hybrid system technique that analyze for proteins interacting
with specific DNA sequences
Note publique d''information :
Variations on the two-hybrid system technique that analyze for mutations or small
molecules that interfere with or dissociate specific protein-DNA interactions
Note publique d''information :
Variations on the two-hybrid system technique that analyze for mutations or small
molecules that interfere with or dissociate specific protein-protein interactions
Note publique d''information :
Variations on the two-hybrid system technique that analyze for proteins that interact
with specific RNA molecules
Note publique d''information :
Variations on the two-hybrid system technique
Note publique d''information :
Variations on the two-hybrid system technique that analyze for mutations or small
molecules that interfere with or dissociate specific interactions between protein
and RNA molecules or other ligands