A broad group of eukaryotic six-transmembrane cation channels that are classified
by sequence homology because their functional involvement with SENSATION is varied.
They have only weak voltage sensitivity and ion selectivity. They are named after
a DROSOPHILA mutant that displayed transient receptor potentials in response to light.
A 25-amino-acid motif containing a TRP box (EWKFAR) just C-terminal to S6 is found
in TRPC, TRPV and TRPM subgroups. ANKYRIN REPEATS are found in TRPC, TRPV & TRPN subgroups.
Some are functionally associated with TYROSINE KINASE or TYPE C PHOSPHOLIPASES
Note générale sur le champ d'application :
note entry terms: TRP refers to transient receptor potential not TRYPTOPHAN
Point d'accès autorisé parallèle
Transient Receptor Potential Channels
Identifiants externes
Identifiant MeSH : mesD050051
Utilisation dans FMeSH
Qualificatifs autorisés : IP / IM / PK / BI / PH / TU / AG / BL / CF / CS / DF / CH
/ DE / UR / RE / HI / AN / CL / EC / GE / PD / ST / AD / AI / SD / UL / PO / AE /
TO / ME2006
Informations sur la notice
Identifiant de la notice : 114599084
RCR créateur de la notice : 0004
Date de création : 30-06-2005
RCR dernier modificateur de la notice : 4994
Date de dernière modification : 20-03-2024 à 10 h 26