Identifiant pérenne de la notice : 21162599X
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Note publique d'information : Current Advances in Osteosarcoma summarizes molecular and genetic characteristics,
new therapeutic ideas, and biological characteristics that have been uncovered in
this field over the past 10 years. Osteosarcoma is an aggressive malignant neoplasm
and is the most common histological form of bone cancer. Osteosarcoma accounts for
approximately 56% of new bone tumors, making it the most primary malignant bone tumor
in children and adolescents. The lungs are the most common site of metastases and
once osteosarcoma spreads to the lungs, it is very difficult to treat. In order
to improve the outcome of this disease, the biology of osteosarcoma needs to be better
understood. There are numerous investigators around the world who have made seminal
discoveries about the important molecular pathways and genetic alterations that contribute
to the development and metastases of osteosarcoma. Other investigators have proposed
novel therapeutic strategies including some based on the molecular and genetic phenotype
of the disease. This volume will provide a comprehensive review of these new discoveries
in one singular text, which will help move the field forward
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