Identifiant pérenne de la notice : 212500198
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Note publique d'information : Following reviews on sleep physiology, regulation, pharmacology, and the neuronal
networks regulating sleep and awakening, as well as a classification of sleep disorders,
this book presents a number of major breakthroughs in the treatment of those disorders.
These include recently approved drugs for treating insomnia, such as Doxepin; variations
on previously approved molecules, e.g. Zolpidem sublingual preparation; or new chemical
entities in advanced stages of clinical development, e.g. Orexin antagonists. Further
topics discussed include drugs acting on the GABA receptor, such as Lorediplon and
Eszopiclone; the treatment of excessive daytime drowsiness with cell therapy and drugs
such as Modafinil, Armodafinil and Sodium oxybate; and the use of Tasimelteon in the
treatment of circadian sleep disorders
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