Identifiant pérenne de la notice : 223657468
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Note publique d'information : "Tight junctions between epithelial and endothelial cells form selective barriers.
However, some tight junction proteins form ion or water channels that conduct through
the otherwise sealed barrier between epithelial cells. Owning to this function they
regulate paracellular transport of solutes, immune cells, and drugs. In various diseases
tight junction proteins can be either up- or downregulated, and by this they aggravate,
or even induce, pathogenesis. This special issues is the first of two presenting reviews
and original research on tight junctions"
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