{"record":{"leader":"cx  r22     2  45","datafield":[{"ind2":" ","ind1":" ","subfield":{"code":"a","content":"20200708afrey50      ba0"},"tag":100},{"ind2":" ","ind1":" ","subfield":[{"code":"a","content":"fre"},{"code":2,"content":"639-2"}],"tag":101},{"ind2":" ","ind1":" ","subfield":{"code":"a","content":2006},"tag":103},{"ind2":" ","ind1":" ","subfield":[{"code":"a","content":"k"},{"code":"f","content":"fre"}],"tag":104},{"ind2":" ","ind1":" ","subfield":[{"code":"a","content":0},{"code":"b","content":"#"},{"code":"c","content":"#"}],"tag":106},{"ind2":" ","ind1":" ","subfield":{"code":"a","content":"AFNOR"},"tag":152},{"ind2":" ","ind1":" ","subfield":{"code":"a","content":"Oeuvre Textuelle"},"tag":189},{"ind2":" ","ind1":" ","subfield":[{"code":7,"content":"ba0yba0"},{"code":"t","content":"La modélisation mathématique dans le cadre de la préparation contre une épidémie d'origine malveillante, application à la fièvre hémorragique Ebola et à la variole"}],"tag":241},{"ind2":" ","ind1":" ","subfield":[{"code":7,"content":"ba0yba0y"},{"code":"a","content":"Dans le cadre de la préparation contre le bioterrorisme, sont présentés des travaux concernant la fièvre hémorragique Ebola (FHE) et la variole. A propos de la FHE Le nombre de reproduction de base (R0) de la FHE a été estimé en ajustant un modèle mathématique de diffusion de la FHE aux données de morbidité de deux épidémies d\u2019origine naturelle. L\u2019estimation était de 2,7 [1,9 ; 2,8] pour l\u2019une et de 2,7 [2,5 ; 4,1] pour l\u2019autre. Les parts du R0 attribuables à la transmission dans la communauté, pendant l\u2019hospitalisation et après le décès ont été estimées. A propos de la variole D\u2019après une analyse de sensibilité de deux modèles compartimentaux de diffusion de la variole (l\u2019un stochastique, l\u2019autre déterministe géographique), il semble que la réduction du délai de mise en place des interventions et la vaccination en anneau aurait un impact sur la taille des épidémies. En revanche, la restriction des flux de transports entre les régions françaises aurait peu d\u2019impact sur la taille globale des épidémies. Un modèle tenant compte de l\u2019effet de l\u2019immunité résiduelle liée à la vaccination dans le passé sur la dynamique épidémique de la variole est également présenté."}],"tag":300},{"ind2":0,"ind1":" ","subfield":[{"code":"b","content":"Thèse de doctorat"},{"code":"c","content":"Santé publique. Épidémiologie et sciences de l'information biomédicale"},{"code":"e","content":"Paris 6"},{"code":"d","content":2006}],"tag":328},{"ind2":" ","ind1":" ","subfield":[{"code":7,"content":"ba0yba0"},{"code":"t","content":"Mathematical modelling and the preparedness against bioterrorist attacks, application to Ebola hemorrhagic fever and smallpox"}],"tag":441},{"ind2":1,"ind1":" ","subfield":[{"code":3,"content":111139988},{"code":7,"content":"ba0yba01"},{"code":"a","content":"Legrand"},{"code":"b","content":"Judith"},{"code":"f","content":"1979-...."},{"code":4,"content":"070"}],"tag":501},{"ind2":1,"ind1":" ","subfield":[{"code":3,"content":"035602031"},{"code":7,"content":"ba0yba04"},{"code":"a","content":"Flahault"},{"code":"b","content":"Antoine"},{"code":"c","content":"médecin"},{"code":4,"content":727}],"tag":501},{"ind2":2,"ind1":0,"subfield":[{"code":3,"content":"027787087"},{"code":7,"content":"ba0yba04"},{"code":"a","content":"Université Pierre et Marie Curie"},{"code":"c","content":"Paris"},{"code":"c","content":"1971-2017"},{"code":4,"content":295}],"tag":511},{"ind2":" ","ind1":" ","subfield":[{"code":7,"content":"ba0yba0"},{"code":3,"content":"027253139"},{"code":"a","content":"Thèses et écrits académiques"},{"code":2,"content":"rameau"}],"tag":608},{"ind2":" ","ind1":2,"subfield":{"code":"a","content":"Mathématique, modèle"},"tag":610},{"ind2":" ","ind1":2,"subfield":{"code":"a","content":"Epidémiologie"},"tag":610},{"ind2":" ","ind1":2,"subfield":{"code":"a","content":"Bioterrorisme"},"tag":610},{"ind2":" ","ind1":2,"subfield":{"code":"a","content":"Variole"},"tag":610},{"ind2":" ","ind1":2,"subfield":{"code":"a","content":"Fièvre hémorragique Ebola"},"tag":610},{"ind2":" ","ind1":" ","subfield":[{"code":"a","content":610},{"code":2,"content":"TEF"}],"tag":686},{"ind2":3,"ind1":" ","subfield":[{"code":"a","content":"FR"},{"code":"b","content":"Abes"},{"code":"c","content":20231218},{"code":"g","content":"AFNOR"}],"tag":801}],"controlfield":[{"tag":"001","content":247856487},{"tag":"003","content":"http://www.idref.fr/247856487"},{"tag":"004","content":20200708},{"tag":"005","content":20231218031016},{"tag":"006","content":"0499"},{"tag":"007","content":"0499"},{"tag":"008","content":"Tr2"}]}}