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Note publique d'information : This self-contained textbook covers fundamental aspects of sequence analysis in evolutionary
biology, including sequence alignment, phylogeny reconstruction, and coalescent simulation.
It addresses these aspects through a series of over 400 computer problems, ranging
from elementary to research level, to enable learning by doing. Students solve the
problems in the same computational environment used for decades in science – the UNIX
command line. This is available on all three major operating systems for PCs: Microsoft
Windows, Mac-OSX, and Linux. To learn using this powerful system, students analyze
sample sequence data by applying generic tools, bioinformatics software, and over
40 programs specifically written for this course. The solutions for all problems are
included, making the book ideal for self-study. Problems are grouped into sections
headed by an introduction and a list of new concepts and programs. By using practical
computing to explore evolutionary concepts and sequence data, the book enables readers
to tackle their own computational problems.
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