Diseases characterized by a selective degeneration of the motor neurons of the spinal
cord, brainstem, or motor cortex. Clinical subtypes are distinguished by the major
site of degeneration. In AMYOTROPHIC LATERAL SCLEROSIS there is involvement of upper,
lower, and brainstem motor neurons. In progressive muscular atrophy and related syndromes
(see MUSCULAR ATROPHY, SPINAL) the motor neurons in the spinal cord are primarily
affected. With progressive bulbar palsy (BULBAR PALSY, PROGRESSIVE), the initial degeneration
occurs in the brainstem. In primary lateral sclerosis, the cortical neurons are affected
in isolation. (Adams et al., Principles of Neurology, 6th ed, p1089)
Note générale sur le champ d'application :
general or unspecified; prefer specifics
Point d'accès autorisé parallèle
Motor Neuron Disease
Identifiants externes
Identifiant MeSH : mesD016472
Utilisation dans FMeSH
Qualificatifs autorisés : DI / PS / IM / MI / DG / PP / RH / EN / ET / MO / EP / BL
/ CF / CI / CN / DH / DT / TH / PX / UR / VI / VE / HI / CL / EC / EM / GE / NU /
RT / EH / PC / PA / ME / CO / SU92
Informations sur la notice
Identifiant de la notice : 040813053
RCR créateur de la notice : 0001
Date de création : 23-09-1998
RCR dernier modificateur de la notice : 4994
Date de dernière modification : 26-11-2024 à 13 h 48